Sermorelin (5mg) Dosage Protocol
Sermorelin is a synthetic GHRH (1-29) analog that was FDA-approved for pediatric growth hormone deficiency. It stimulates natural GH release from the pituitary gland.
Add 2.0 mL bacteriostatic water → 2.5 mg/mL (2500 mcg/mL)
200-300 mcg nightly, 5-7 nights per week
At 2.5 mg/mL: 8 units = 200 mcg, 12 units = 300 mcg
Lyophilized: -20°C; Reconstituted: 2-8°C for up to 4 weeks
| Week | Daily Dose | Units (per injection) |
|---|---|---|
| Weeks 1-2 | 200 mcg nightly | 8 units (0.08 mL) |
| Weeks 3-8 | 300 mcg nightly | 12 units (0.12 mL) |
| Weeks 9-12+ | 300 mcg nightly | 12 units (0.12 mL) |
- 1Draw 2.0 mL bacteriostatic water with a sterile syringe
- 2Inject slowly down the vial wall to prevent foaming
- 3Gently swirl until fully dissolved - do not shake
- 4Label with date and concentration, refrigerate immediately
Sermorelin is a truncated GHRH analog (first 29 amino acids) that stimulates the pituitary to release growth hormone naturally. Clinical studies used 30 mcg/kg bodyweight at bedtime. It works with the body's natural feedback mechanisms, unlike exogenous GH.
- Stimulates natural GH release
- Preserves pituitary function
- May improve sleep quality
- Supports recovery and body composition
- Prakash A, Goa KL. Sermorelin: a review. Drugs. 1999;58(5):881-98
- FDA Prescribing Information - Sermorelin acetate
- Clinical studies of sermorelin in growth hormone deficiency
Lyophilized
Store at -20°C, protected from light
Reconstituted
Refrigerate at 2-8°C, use within 4 weeks
Best administered at bedtime for optimal GH release
- •Previously FDA-approved for pediatric GHD
- •Best administered at bedtime
- •Fasting enhances GH release response
- •Often combined with GHRP for synergy
Disclaimer: This content is intended for research and educational purposes only. Not intended to diagnose, treat, cure, or prevent any disease. All compounds are for research use only. Dosing information is derived from published scientific literature and clinical studies.