Selank (5mg) Dosage Protocol
Selank is a synthetic heptapeptide analog of tuftsin with anxiolytic and nootropic properties. It is approved in Russia for anxiety and cognitive enhancement. It does not cause sedation or dependence.
Add 5.0 mL bacteriostatic water → 1 mg/mL (1000 mcg/mL)
250-500 mcg intranasally or subcutaneously, 2-3x daily
At 1 mg/mL: 25 units = 250 mcg, 50 units = 500 mcg
Lyophilized: -20°C; Reconstituted: 2-8°C for up to 4 weeks
| Week | Daily Dose | Units (per injection) |
|---|---|---|
| Daily | 250-500 mcg | 2-3 times daily |
| Intranasal | 2700 mcg/day | Clinical trial dose |
| Duration | 14-21 days | Per cycle |
- 1Draw 5.0 mL bacteriostatic water with a sterile syringe
- 2Inject slowly down the vial wall to prevent foaming
- 3Gently swirl until fully dissolved - do not shake
- 4Label with date and concentration, refrigerate immediately
Selank modulates GABA-A receptor function and affects serotonin metabolism. It enhances BDNF expression and has immunomodulatory effects through IL-6 regulation. Clinical studies used 2700 mcg/day intranasally. Effects are comparable to low-dose benzodiazepines without sedation or dependence.
- Anxiolytic effects without sedation
- Nootropic and cognitive enhancement
- No dependence or withdrawal symptoms
- Immunomodulatory properties
- Kasian A, et al. Selank enhances diazepam effects. Behav Brain Res. 2017;319:64-70
- Volkova A, et al. Selank affects gene expression. Mol Genet Genomics. 2016;291(2):647-53
- Vyunova TV, et al. Peptide-based anxiolytics. Protein Pept Lett. 2018;25(10):914-23
- Syunyakov T, et al. Selank in anxiety disorders. Eur Psychiatry. 2012;27(Suppl 1):1
Lyophilized
Store at -20°C, protected from light
Reconstituted
Refrigerate at 2-8°C, use within 4 weeks
Intranasal administration is common in clinical use
- •Approved in Russia for anxiety disorders
- •Does not cause sedation or cognitive impairment
- •No known drug interactions
- •May be combined with other nootropics
Disclaimer: This content is intended for research and educational purposes only. Not intended to diagnose, treat, cure, or prevent any disease. All compounds are for research use only. Dosing information is derived from published scientific literature and clinical studies.