Single Peptide5mgResearch-Based Protocol

Ipamorelin (5mg) Dosage Protocol

Ipamorelin is a selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin. It is considered one of the safest GHRPs.

Quickstart Highlights
Reconstitute

Add 2.0 mL bacteriostatic water → 2.5 mg/mL (2500 mcg/mL)

Daily Range

200-300 mcg, 2-3 times daily

Easy Measuring

At 2.5 mg/mL: 8 units = 200 mcg, 12 units = 300 mcg

Storage

Lyophilized: -20°C; Reconstituted: 2-8°C for up to 4 weeks

Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing based on research literature
WeekDaily DoseUnits (per injection)
Weeks 1-4200 mcg 2x daily8 units per dose
Weeks 5-8200 mcg 3x daily8 units per dose
Weeks 9-12300 mcg 2-3x daily12 units per dose
Reconstitution Steps
  1. 1Draw 2.0 mL bacteriostatic water with a sterile syringe
  2. 2Inject slowly down the vial wall to prevent foaming
  3. 3Gently swirl until fully dissolved - do not shake
  4. 4Label with date and concentration, refrigerate immediately
How This Works

Ipamorelin is a pentapeptide that selectively stimulates growth hormone release through the ghrelin receptor. Unlike other GHRPs, it does not significantly increase cortisol, prolactin, or appetite. Clinical trials (NCT01280344) evaluated its use for post-operative GI recovery.

Potential Benefits & Effects
Observations from preclinical and clinical literature
  • Selective GH release without cortisol/prolactin increase
  • Supports recovery and sleep quality
  • May improve body composition
  • Well-tolerated with minimal side effects
Scientific References
Published research supporting this protocol
  1. Raun K, et al. Ipamorelin, the first selective GH secretagogue. Eur J Endocrinol. 1998;139(5):552-61
  2. ClinicalTrials.gov NCT01280344 - Ipamorelin for postoperative ileus
  3. Prospective study of ipamorelin in bowel resection. Int J Colorectal Dis. 2014
Storage Instructions

Lyophilized

Store at -20°C, protected from light

Reconstituted

Refrigerate at 2-8°C, use within 4 weeks

Best administered on empty stomach for optimal GH release

Important Notes
  • Research compound - not FDA approved
  • Best combined with GHRH (like CJC-1295) for synergy
  • Fasting enhances GH release response
  • Timing: morning, post-workout, and before bed optimal

Disclaimer: This content is intended for research and educational purposes only. Not intended to diagnose, treat, cure, or prevent any disease. All compounds are for research use only. Dosing information is derived from published scientific literature and clinical studies.