IGF-1 LR3 (1mg) Dosage Protocol
IGF-1 LR3 (Long R3 IGF-1) is a modified version of insulin-like growth factor-1 with an extended half-life. The arginine substitution and 13 amino acid extension reduce binding to IGF binding proteins.
Add 1.0 mL bacteriostatic water → 1 mg/mL (1000 mcg/mL)
20-60 mcg daily, post-workout or split doses
At 1 mg/mL: 2 units = 20 mcg, 6 units = 60 mcg
Lyophilized: -20°C; Reconstituted: 2-8°C for up to 4 weeks
| Week | Daily Dose | Units (per injection) |
|---|---|---|
| Weeks 1-2 | 20 mcg daily | 2 units post-workout |
| Weeks 3-4 | 40 mcg daily | 4 units post-workout |
| Weeks 5-6 | 50-60 mcg daily | 5-6 units post-workout |
- 1Draw 1.0 mL bacteriostatic water with a sterile syringe
- 2Inject slowly down the vial wall to prevent foaming
- 3Gently swirl until fully dissolved - do not shake
- 4Label with date and concentration, refrigerate immediately
IGF-1 LR3 has reduced affinity for IGF binding proteins, resulting in longer half-life and greater bioavailability than native IGF-1. It activates the IGF-1 receptor, promoting protein synthesis, cell growth, and nutrient uptake in muscle tissue.
- Extended half-life vs native IGF-1
- Promotes protein synthesis
- May support muscle hyperplasia
- Enhanced nutrient partitioning
- Francis GL, et al. Novel recombinant IGF-1 analogs. Endocrinology. 1992
- Tomas FM, et al. Effects of IGF-1 on muscle. J Endocrinol. 1993
- IGF-1 LR3 research and muscle protein synthesis studies
Lyophilized
Store at -20°C, protected from light
Reconstituted
Refrigerate at 2-8°C, use within 4 weeks
Cycle on/off to prevent receptor desensitization
- •Research compound - not FDA approved
- •May cause hypoglycemia - monitor blood sugar
- •Cycle 4-6 weeks on, 4 weeks off
- •Start with lowest effective dose
Disclaimer: This content is intended for research and educational purposes only. Not intended to diagnose, treat, cure, or prevent any disease. All compounds are for research use only. Dosing information is derived from published scientific literature and clinical studies.